CHONDROITIN SULFATE B SODIUM SALT

CHONDROITIN SULFATE B SODIUM SALT 화학적 특성, 용도, 생산

• 화학적 성질

  Also available: fractionated dermatan sulfates with Av. Mw 25,000 ± 2,500 and 50,000 ± 5,000 and different Anti-Xa and Anti-IIa activities. Please inquire

• 용도

  Antithrombotic.

• 일반 설명

  Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.

• Purification Methods

  Dermatan sulfate is purified by digestion with papain and hyaluronidase, and fractionation using aqueous EtOH. [Gifonelli & Roden Biochemical Preparations 12 1 1968.]

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