Methyltrienolone

한글명:Methyltrienolone

카스 번호965-93-5

상품명:Methyltrienolone

CBNumberCB3221633

분자식C19H24O2

포뮬러 무게284.39

MOL 파일965-93-5.mol

화학적 성질

녹는점	170°
알파	D20 -58.7° (c = 0.5 in ethanol)
끓는 점	485.9±45.0 °C(Predicted)
밀도	1.17±0.1 g/cm3(Predicted)
저장 조건	2-8°C
용해도	DMSO: ≥10mg/mL
산도 계수 (pKa)	14.79±0.40(Predicted)
물리적 상태	가루
색상	밝은 노란색에서 노란색까지
optical activity	[α]/D -48 to -68°
InChI	InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/s3
InChIKey	CCCIJQPRIXGQOE-XWSJACJDSA-N
SMILES	[C@@]12([H])CC[C@@](O)(C)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] \|&1:0,4,7,21,r\|
CAS 데이터베이스	965-93-5(CAS DataBase Reference)

위험 및 안전 성명

WGK 독일	3
DEA Controlled Substances	CSCN: 4000 CSA SCH: Schedule III NARC: No

그림문자(GHS)

Methyltrienolone 화학적 특성, 용도, 생산

개요
Methyltrienolone 원료 분말은 매우 남성 호르몬이며 이러한 효과가있는 사람들에게는 탈모와 심한 여드름을 일으킬 수 있습니다. Methyltrienolone 원료 분말의 프로게스테론 효과로 인해 여성형 유방이 위험합니다. Methyltrienolone 원료 분말의 가장 큰 관심사는 아마도 간 독성 일 것입니다.
개요
Methyltrienolone, also called metribolone, is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug or a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and prostatic tumors.
화학적 성질
Pale Yellow Solid
용도
Methyltrienolone is a synthetic derivative of testosterone that is used in the medical field as an androgen and anabolic agent. It has been used to treat breast cancer, prostate cancer, and other cancers that are sensitive to hormones.
정의
ChEBI: Methyltrienolone, also known as 7beta-hydroxy-17-methylestra-4,9,11-trien-3-one, is a synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. It has a role as an androgen. It is an anabolic androgenic steroid, a 17beta-hydroxy steroid and a 3-oxo steroid. It derives from a hydride of an estrane.
참고 문헌
https://en.wikipedia.org/wiki/Metribolone
https://www.drugbank.ca/drugs/DB02998
https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone
Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg

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