바말루졸

바말루졸 화학적 특성, 용도, 생산

• Originator

  Bamaluzole,Onbio Inc.

• Manufacturing Process

  1-Chlorophenyl-2-methanol is dissolved in dimethylformamide; NaH is added and the mixture is stirred at 20°C for 1 h. After a solution of 4-chloro-1- methyl-1H-imidazo[4,5-c]pyridine [melting point 132°-134°C; obtainable by reaction of 4-methylamino-3-nitropyridine with HCl/SnCl2 to give 3-amino-2- chloro-4-methylaminopyridine (melting point 170°-173°C) and reaction with HCOOH/acetic anhydride] in dimethylformamide has been added, the mixture is stirred at 90°-95°C for 15 h. The mixture is evaporated and the residue is worked up in the customary manner to give 4-o-chlorobenzyloxy-1-methyl- 1H-imidazo[4,5-c]pyridine, melting point 132°-135°C (crystallize from ethyl acetate-tetrahydofuran).

• Therapeutic Function

  Anticonvulsant

바말루졸 준비 용품 및 원자재

바말루졸 공급 업체

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