ambenoxan

ambenoxan 화학적 특성, 용도, 생산

• Originator

  Ambenoxan,ZYF Pharm Chemical

• Manufacturing Process

  2-Aminomethyl-1,4-benzodioxane (17 g) and β-methoxyethoxy ethyl chloride (7 g) were heated at 160°C for 2 hours. The reaction mixture was cooled and chloroform (30 ml) and a solution of potassium carbonate (7 g) in water (20 ml) added thereto.The chloroform layer was removed and the aqueous layer extracted twice with chloroform (10 ml each time). The chloroform extracts were combined and dehydrated over anhydrous sodium sulfate. Filtration, followed by distillation gave 2-(β-methoxyethoxyethyl)amino-methyl-1,4- benzodioxane (yield 7.7 g) as a pale yellow oil boiling at 180-186°C/11.5 mm.
  The base was converted to a white hydrochloride having a melting point of 104-106°C by the addition of alcoholic hydrogen chloride to an ether solution of the base and isolation of the salt which separated.

• Therapeutic Function

  Muscle relaxant

ambenoxan 준비 용품 및 원자재

ambenoxan 공급 업체

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