6-아미노플루오레세인

한글명:6-아미노플루오레세인

카스 번호51649-83-3

상품명:6-Aminofluorescein

CBNumberCB2300526

분자식C20H13NO5

포뮬러 무게347.32

MOL 파일51649-83-3.mol

동의어(한글)

6-아미노플루오레세인

화학적 성질

녹는점	285 °C (dec.)(lit.)
끓는 점	481.89°C (rough estimate)
밀도	1.3724 (rough estimate)
굴절률	1.5180 (estimate)
저장 조건	2-8°C
용해도	메탄올: 용해성 1mg/mL, 투명, 노란색에서 매우 어두운 노란색-주황색
산도 계수 (pKa)	9.34±0.20(Predicted)
물리적 상태	고체
물리적 상태	단단한 모양
색상	노란색에서 주황색으로
BRN	51708
안정성	빛과 습기에 민감함
InChI	InChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
InChIKey	YOAWSYSKQHLFPM-UHFFFAOYSA-N
SMILES	C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(N)=C1)C(=O)O2
CAS 데이터베이스	51649-83-3(CAS DataBase Reference)

위험 및 안전 성명

위험품 표기

위험 카페고리 넘버

36/37/38

안전지침서

26-36

WGK 독일

F 고인화성물질

10-23

HS 번호

29329990

NFPA 704:

	0
1		0

그림문자(GHS)

6-아미노플루오레세인 화학적 특성, 용도, 생산

개요
6-Aminofluorescein (6-AF) is a new fluorescence dye with bright colors and high fluorescence intensity. Its chemical structure history contains a nitrogen group and a fluorescent group. The presence of the fluorescent component enables 6-Aminofluorescein to emit a distinct fluorescent signal when excited, making it valuable for fluorescent labeling and imaging. It is widely used in biological science research, chemical analysis and fluorescence microscopy.
화학적 성질
Yellow Solid
용도
Fluorescent labeling reagent for proteins. Glycosaminoglycuronans react with 6-aminofluorescein to yield fluorescent derivatives. Used in the fluorescent antibody technique for rapid identification of pathogens.
Biological Functions
6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed "buckysomes". 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein. 6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).
참고 문헌
[1] BHARATE G Y, QIN H, FANG J. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging[J]. Journal of Personalized Medicine, 2022, 12. DOI:10.3390/jpm12101650.
[2] Müller, Werner EG, and Heinz Christoph Schr?der, eds. Biological Response Modifiers—Interferons, Double-Stranded RNA and 2′, 5′-Oligoadenylates. Vol. 14. Springer Science & Business Media, 2012.

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