Enoxaparin sodium

한글명:Enoxaparin sodium

카스 번호679809-58-6

상품명:Enoxaparin sodium

CBNumberCB1994513

분자식C57H82N4Na4O53S3

포뮬러 무게0

MOL 파일Mol file

화학적 성질

녹는점	>191°C (dec.)
저장 조건	Room Temperature, Under inert atmosphere
용해도	물(약간 용해됨)
물리적 상태	고체
물리적 상태	단단한 모양
색상	흰색에서 황백색까지

위험 및 안전 성명

HS 번호	3001900190
유해 물질 데이터	679809-58-6(Hazardous Substances Data)

그림문자(GHS)

Enoxaparin sodium 화학적 특성, 용도, 생산

개요
Enoxaparin sodium is the sodium salt of a low-molecular-mass heparin that is obtained by alkaline depolymerisation of the benzyl ester derivative of heparin from porcine intestinal mucosa. Enoxaparin sodium is an antithrombotic agent (ATC code B01AB05) characterized by a higher ratio of antithrombotic activity to anticoagulant activity compared to unfractionated heparin.
Specifically, Enoxaparin sodium as the sodium salt of depolymerized Heparin is subject to characteristic structural modifications from the effects of the depolymerization reaction. Characteristic structures such as partial transformation of glucosamines into mannosamines, formation of 1,6-anydro derivatives and 2,3 epoxide residues with subsequent conversion to galacturonic acid and the change in the proportion of the sulfated and non-sulfated residues are some of the changes that constitute Enoxaparin a structurally difficult to characterize molecule. As such no single technique or parameter is adequate to fully characterize the Enoxaparin molecule as part of a biosimilarity exercise against the reference.
화학적 성질
degree of sulphatation is ~ 2 per disaccharide
용도
Enoxaparin is marketed under the brand name Lovenox and as a generic drug under the name enoxaparin sodium for injection.
Enoxaparin sodium is intended for use in the treatment of deep vein thrombosis; prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, and treatment of acute deep vein thrombosis.
Indications
Enoxaparin sodium is a gold standard for antithrombosis which has the largest number of indications among all LMWHs. Prophylaxis of vein thrombosis diseases (prevent intra-vein thrombosis), treatment of deep venous thrombosis, Prevention of thrombus formation in the in vitro circulation during hemodialysis, treatment of acute unstable angina and non-Q-wave myocardial infarction, administered with Aspirin.

Enoxaparin sodium 공급 업체

Enoxaparin sodium 관련 검색

Send Inquriy