드로모스타놀론

한글명:드로모스타놀론

카스 번호58-19-5

상품명:Drostanolone

CBNumberCB1911442

분자식C20H32O2

포뮬러 무게304.47

MOL 파일58-19-5.mol

동의어(한글)

드로모스타놀론

화학적 성질

녹는점	145-147°C
알파	D +32° (ethanol)
끓는 점	420.3±45.0 °C(Predicted)
밀도	1.058±0.06 g/cm3(Predicted)
저장 조건	Refrigerator
용해도	Acetonitrile: 1 mg/mL; Ethanol: 1 mg/mL; Methanol: 1 mg/mL
물리적 상태	결정성 고체
산도 계수 (pKa)	15.09±0.70(Predicted)
CAS 데이터베이스	58-19-5
NIST	Drostanolone(58-19-5)

위험 및 안전 성명

유해 물질 데이터

58-19-5(Hazardous Substances Data)

드로모스타놀론 화학적 특성, 용도, 생산

개요
Drostanolone, also known as Dromostanolone[58-19-5], is an anabolic hormone and a derivative of methyltestosterone. Its action is similar to that of Conviron. Its anabolic effect is 4 times that of methyltestosterone and its androgenic activity is 0.39 times that of the latter. It is clinically used in the treatment of chronic wasting disease, pediatric underdevelopment, old age and frailty, serious illness and postoperative weakness, osteoporosis, aplastic anemia, leukopenia, thrombocytopenia, and hyperlipidemia.
화학적 성질
White or off-white crystalline powder, odorless. Insoluble in water, slightly soluble in ethanol, slightly soluble in ether, soluble in chloroform.
용도
Drostanolone is a synthetic estrogen antagonist and is classified as an anabolic androgenic steroid. It has been used in sports to improve athletic performance and can be detected in urine. In the United States, Drostanolone is classified as a Schedule III substance, indicating it is regulated and controlled. This product is intended for research and forensic applications.
Mode of action
It can promote protein synthesis and inhibit protein xenobiosis, reduce calcium and phosphorus excretion and alleviate bone marrow suppression, promote growth and development, promote tissue renewal and granulation, and reduce blood cholesterol, and have preventive and antagonistic effects on adrenocorticotropic hormone long-term use of adrenocorticotropic hypoplasia and protein anisotropy.
참고 문헌
[1] SCH?NZER W, DONIKE M. Metabolism of anabolic steroids in man: synthesis and use of reference substances for identification of anabolic steroid metabolites[J]. Analytica Chimica Acta, 1993, 275: 23-48. DOI:10.1016/0003-2670(93)80274-O.
[2] KINTZ P, GHEDDAR L. Evidence of use of drostanolone, an anabolic steroid, at the time the subject committed a murder: Place of hair analysis[J]. Toxicologie Analytique et Clinique, 2021. DOI:10.1016/J.TOXAC.2021.05.002.
[3] LIU Y, LU J, YANG S, et al. New drostanolone metabolites in human urine by liquid chromatography time-of-flight tandem mass spectrometry and their application for doping control[J]. Steroids, 2016, 108: 61-67. DOI:10.1016/j.steroids.2016.01.013.

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