타이로시나아제

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

• 유해·위험 문구

  H334：흡입 시 알레르기성 반응, 천식 또는 호흡 곤란 등을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P284：호흡 보호구를 착용하시오.

  P501：...에 내용물 / 용기를 폐기 하시오.

타이로시나아제 화학적 특성, 용도, 생산

• 용도

  Tyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.

• 일반 설명

  Isoelectric point (pI): 4.7-5
  pH optimum is 6-7
  
  Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.
  
  Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.

• Biochem/physiol Actions

  Converts tyrosine to L-DOPA or tyramine to dopamine

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