메틸(1-트리메틸실릴)아크릴레이트

메틸(1-트리메틸실릴)아크릴레이트 화학적 특성, 용도, 생산

• 물리적 성질

  bp 75 °C/50 mmHg, 152 °C/690 mmHg.

• 용도

  Methyl 2-Trimethylsilylacrylate is widely used as reactive, α-silyl Michael acceptor for conjugate addition of carbanions, enolate anions, organolithium reagents, and Grignard reagents; affords 3-cyclopentenecarboxylates and cyclohexanecarboxylates by [3 + 2] and [4 + 2] annulation methods; provides α-silyl esters and vinylsilanes by organolithium conjugate additions.

• 제조 방법

  Methyl 2-Trimethylsilylacrylate is prepared by the reaction of (E)-2- (trimethylsilyl)vinyllithium with methyl chloroformate or by carbonation of the corresponding Grignard reagent prepared from (1-bromovinyl)trimethylsilane, giving 2-trimethylsilylacrylic acid. The methyl ester is prepared from the acid by direct esterification with absolute methanol in the presence of mineral acid, by reaction with diazomethane at low temperature, or by treatment with BF3·MeOH complex.

메틸(1-트리메틸실릴)아크릴레이트 공급 업체

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