Levomefolate calcium

한글명:Levomefolate calcium

카스 번호151533-22-1

상품명:Levomefolate calcium

CBNumberCB11420680

분자식C20H27CaN7O6

포뮬러 무게501.56

MOL 파일151533-22-1.mol

화학적 성질

녹는점	>300°C
저장 조건	Inert atmosphere,2-8°C
용해도	산성수(가열), 물(약간 용해됨, 가열)
물리적 상태	고체
물리적 상태	단단한 모양
색상	황백색에서 밝은 노란색까지
냄새	100.00%. 냄새 없는
InChIKey	CZDUXPNTZGHMRC-ZPZVDPIKNA-N
SMILES	CN1[C@H](CNC2NC(N)=NC(=O)C1=2)CNC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[Ca] \|&1:2,22,r\|
CAS 데이터베이스	151533-22-1

위험 및 안전 성명

안전지침서	24/25
HS 번호	29339900

그림문자(GHS)

Levomefolate calcium 화학적 특성, 용도, 생산

개요
Levomefolate calcium (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. L-5-methyltetrahydrofolate, also known as levomefolic acid, is the primary biologically active form of folate. It is involved in many important in vivo process including DNAreproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. It can be used for the treatment of major depressive disorder, cardiovascular disease and cancer. It can be used for the treatment of hyperhomocysteinemia regularly found in hemodialysis patients.
화학적 성질
Off-White to Pale Yellow Solid
상표명
Products containing levomefolate calcium Brand name: L-Methylfolate Calcium
Multi-ingredient medications containing levomefolate calcium drospirenone/ethinyl estradiol/levomefolate calcium systemic Brand names: Beyaz, Tydemy, Safyral, Rajani
Biological Functions
Levomefolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.
Clinical Use
Folates are a class of water soluble compounds belonging to the Vitamin B complex which are essential for a number of metabolic functions, including processes involved in the development and metabolism of CNS and the production of DNA and RNA, primarily in infancy, adolescence and pregnancy.
Calcium Levomefolate is the active metabolic form of folates in the body.
Folate deficiency consequences can be as serious as birth defects (i.e. "spina bifida"), megaloblastic anaemia, and some types of depression.
Calcium Levomefolate can be the most effective treatment to remedy those deficiencies.
Calcium Levomefolate is formulated in many medical supplements for cases of folate deficiency or need for increased uptake; it is prescribed during pregnancy to prevent birth defects associated with CNS formation and functionality.
It is also the active ingredient in medicinal products prescribed for certain types of depression, disturbed behaviour and Mild Cognitive Impairment (MCI)

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