SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA

SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA 화학적 특성, 용도, 생산

• 용도

  Substance P acetate salt hydrate has been:
  
  • used as a neurokinin 1 (NK1) receptor agonist for the activation of spinal nociceptive circuitry in mice
  • administered in central nucleus (ACE) in rat to study its positive reinforcing effects
  • used as an inhibitor of myosin light chain kinase in isolated lymphatic vessels from rat
  
  

• 일반 설명

  Substance P is a small peptide produced by macrophages, lymphocytes, eosinophils, dendritic cells and nerves. It is part of the neurokinin group.

• Biochem/physiol Actions

  NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.

SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA 공급 업체

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