부테타메이트

부테타메이트 화학적 특성, 용도, 생산

• Originator

  Butetamat-dihydrogencitrat,Chemische Werke Hommel GmbH and Co.KG

• Manufacturing Process

  16.4 parts of alpha-phenylbutiric acid, 17.5 parts of beta-diethylaminoethylchloride hydrochloride and 35 parts of dry potassium carbonate in 60 parts diisopropyl ether was stirred for 18 hours under reflux. To the reaction mixture at 40°C was added 120 parts of the water. Organic layer was washed with the water. The solvent was removed and the 2- (diethylamino)ethyl-2-phenylbutyrate was distilled at 167-168°C/10 mm; melting point of hydrochloride 167-169°C.
  In practice it is usually used as citrate.

• Therapeutic Function

  Anticholinergic, Spasmolytic, Antitussive

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