염화벤잘코늄

한글명:염화벤잘코늄

카스 번호8001-54-5

상품명:Benzalkonium chloride

CBNumberCB0712969

분자식C17H30ClN

포뮬러 무게283.88

MOL 파일8001-54-5.mol

동의어(한글)

네오-저미톨

디만닌

비오놀

화학적 성질

끓는 점	>100°C/760mmHg
밀도	0.98
저장 조건	Store below +30°C.
용해도	물과 에탄올(96%)에 매우 잘 녹습니다. 산성 수용액을 흔들면 거품이 많이 납니다.
물리적 상태	점성 용액
Specific Gravity	0.98
색상	투명하거나 흰색에서 노란색까지, 노란색-흰색 조각이 포함될 수 있음
안정성	안정적인. 강한 산화제, 습기와 호환되지 않습니다. 흡습성.
InChI	InChI=1S/C10H16N.ClH/c1-11(2,3)9-10-7-5-4-6-8-10;/h4-8H,9H2,1-3H3;1H/q+1;/p-1
InChIKey	KXHPPCXNWTUNSB-UHFFFAOYSA-M
SMILES	C1C=C(C[N+](C)(C)C)C=CC=1.[Cl-]
LogP	1.692 (est)
CAS 데이터베이스	8001-54-5(CAS DataBase Reference)
EPA	Benzalkonium chloride (8001-54-5)

위험 및 안전 성명

위험품 표기	C,N
위험 카페고리 넘버	21/22-34-50
안전지침서	36/37/39-45-61
유엔번호(UN No.)	UN 3261 8/PG 3
WGK 독일	3
RTECS 번호	BO3151000
F 고인화성물질	3-9
HS 번호	34021200
유해 물질 데이터	8001-54-5(Hazardous Substances Data)
독성	LD50 orally in rats: 400 mg/kg (Cummins, Kimura)

그림문자(GHS)

그림문자(GHS)
신호 어

Danger
유해·위험 문구

H302：삼키면 유해함

H312：피부와 접촉하면 유해함

H314：피부에 심한 화상과 눈에 손상을 일으킴

H318：눈에 심한 손상을 일으킴

H332：흡입하면 유해함
예방조치문구

P260：분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.

P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

P264：취급 후에는 손을 철저히 씻으시오.

P264：취급 후에는 손을 철저히 씻으시오.

P270：이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.

P271：옥외 또는 환기가 잘 되는 곳에서만 취급하시오.

P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

P301+P312：삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.

P301+P330+P331：삼켰다면 입을 씻어내시오. 토하게 하려 하지 마시오.

P302+P352：피부에 묻으면 다량의 물로 씻으시오.

P303+P361+P353：피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.

P304+P340：흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.

P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

P310：즉시 의료기관(의사)의 진찰을 받으시오. 삼켰다면 즉시 의료기관(의사)의 도움을 받으시오.

P312：불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.

P321：(…) 처치를 하시오.

P322：특정 조치(라벨의 … 참조)

P330：입을 씻어내시오.

P363：다시 사용전 오염된 의류는 세척하시오.

P405：밀봉하여 저장하시오.

P501：...에 내용물 / 용기를 폐기 하시오.

염화벤잘코늄 MSDS

염화벤잘코늄 화학적 특성, 용도, 생산

개요
Benzalkonium chloride is a quaternary ammonium mixture of alkyl, dimethyl and benzyl ammonium chlorides.It is an irritant rather than a sensitizer, but may cause contact dermatitis in nursing and medical personnel. An unusual case was reported in a farm worker who used a detergent containing benzalkonium chloride to clean the piggery.
화학적 성질
Benzalkonium chloride occurs as a white or yellowish-white amorphous powder, a thick gel, or gelatinous flakes. It is hygroscopic, soapy to the touch, and has a mild aromatic odor and very bitter taste.
용도
benzalkonium chloride is a preservative with anti-microbial and deodorant properties. It can also be used as a surfactant. With continuous use, it may cause occasional allergic reactions.
정의
ChEBI: A class of quaternary ammonium chloride salts in which the nitrogen is substituted by a benzyl group, two methyl groups and an even-numbered alkyl chain.
생산 방법
Benzalkonium chloride is formed by the reaction of a solution of Nalkyl- N-methylbenzamine with methyl chloride in an organic solvent suitable for precipitating the quaternary compound as it is formed.
위험도
Highly toxic; poison.
Pharmaceutical Applications
Benzalkonium chloride is a quaternary ammonium compound used in pharmaceutical formulations as an antimicrobial preservative in applications similar to other cationic surfactants, such as cetrimide. In ophthalmic preparations, benzalkonium chloride is one of the most widely used preservatives,at a concentration of 0.01–0.02% w/v. Often it is used in combination with other preservatives or excipients, particularly 0.1% w/v disodium edetate, to enhance its antimicrobial activity against strains of Pseudomonas.
In nasal, and otic formulations a concentration of 0.002–0.02% w/v is used, sometimes in combination with 0.002–0.005% w/v thimerosal. Benzalkonium chloride 0.01% w/v is also employed as a preservative in small-volume parenteral products. Benzalkonium chloride was also shown to enhance the topical penetration of lorazepam.
Benzalkonium chloride is additionally used as a preservative in cosmetics.
농업용
Biocide, Algaecide, Fungicide: Used as an algaecide to control slime mold, algae, fish pathogens, and mollusks in ponds, canals and bodies of water. Also widely used in deodorants, detergents, sanitizers and germicides for applications in food plants, laundries, and operating rooms. Not listed for use in EU countries . Registered for use in the U.S. but not California.
상품명
AMMONYX®; ARQUAD DMMCB-75®; BARQUAT® MB-50; BARQUAT® MB-80; BAYCLEAN®; BIO-QUAT 50-24®; CATAMINE® AB; CONSAN®; DRAPOLENE®; GARDIQUAT®-1450; HYAMINE®-3500; INTEXAN® LB-50; KATAMINE® AB; NEO GERM-I-TOL®; ONYX BTC; OSVAN; RODALON®; SENTINEL®; TRITON® K-60; VIKROL® RQ
색상 색인 번호
This quaternary ammonium cationic surfactant is a mixture of alkyl, dimethyl, and benzyl ammonium chlorides (-R). It is an irritant rather than a sensitizer, but may cause allergic contact dermatitis from creams, detergents/antiseptics, ophthalmic preparations, and in nursing, veterinary, dental, and medical personnel. Its presence was observed in plaster of Paris.
Clinical Use
Alkylbenzyldimethylammonium chloride (Zephiran) is a mixtureof alkylbenzyldimethylammonium chlorides of the generalformula [C6H5CH2N(CH3)2R] Cl , where R represents amixture of alkyl chains beginning with C8H17 and extendingto higher homologues with C12H25, C14H29, and C16H33. The higher–molecular-weight homologues compose the majorfractions. Although variations in the physical and antimicrobialproperties exist between individual members of the mixture,they are of little importance in the chemistry of the overallproduct. Benzalkonium chloride occurs as a white gel thatis soluble in water, alcohol, and organic solvents. Aqueous solutionsare colorless, slightly alkaline, and very foamy.
Benzalkonium chloride is a detergent, an emulsifier, anda wetting agent. It is used as an antiseptic for skin and mucousmembranes in concentrations of 1:750 to 1:20,000. Forirrigation, 1:20,000 to 1:40,000 concentrations are used. Forstorage of surgical instruments, 1:750 to 1:5,000 concentrationsare used, with 0.5% NaNO3 added as a preservative.
부작용
Clinically, benzalkonium chloride may cause eye irritation and is known to discolour soft contact lenses. Benzalkonium chloride in eye drops has also been reported to cause punctate keratopathy and/or toxic ulcerative keratopathy, especially in frequent or prolonged use or in conditions where the cornea is compromised.
저장
Benzalkonium chloride is hygroscopic and may be affected by light, air, and metals.
Solutions are stable over a wide pH and temperature range and may be sterilized by autoclaving without loss of effectiveness. Solutions may be stored for prolonged periods at room temperature. Dilute solutions stored in polyvinyl chloride or polyurethane foam containers may lose antimicrobial activity.
The bulk material should be stored in an airtight container, protected from light and contact with metals, in a cool, dry place.
비 호환성
Incompatible with aluminum, anionic surfactants, citrates, cotton, fluorescein, hydrogen peroxide, hypromellose,iodides, kaolin, lanolin, nitrates, nonionic surfactants in high concentration, permanganates, protein, salicylates, silver salts, soaps, sulfonamides, tartrates, zinc oxide, zinc sulfate, some rubber mixes, and some plastic mixes.
Benzalkonium chloride has been shown to be adsorbed to various filtering membranes, especially those that are hydrophobic or anionic.
Regulatory Status
Included in the FDA Inactive Ingredients Database (inhalations, IM injections, nasal, ophthalmic, otic, and topical preparations). Included in nonparenteral medicines licensed in the UK. It is also included in the Canadian List of Acceptable Non-medicinal Ingredients.

염화벤잘코늄 준비 용품 및 원자재

염화벤잘코늄 공급 업체

염화벤잘코늄 관련 검색

Send Inquriy