Human Menopausal Gonadotrophin

한글명:Human Menopausal Gonadotrophin

카스 번호61489-71-2

상품명:Human Menopausal Gonadotrophin

CBNumberCB0685654

분자식C9H18O

포뮬러 무게142.23862

MOL 파일61489-71-2.mol

화학적 성질

저장 조건	2-8°C
InChI	InChI=1S/C9H18O/c1-9(2,3)7-5-4-6-8-10/h8H,4-7H2,1-3H3
InChIKey	CBUWTGCATVNMJE-UHFFFAOYSA-N
SMILES	C(=O)CCCCC(C)(C)C
CAS 데이터베이스	61489-71-2(CAS DataBase Reference)
EPA	Menotropins (61489-71-2)

위험 및 안전 성명

위험품 표기	B
WGK 독일	3
RTECS 번호	MT6425640

Human Menopausal Gonadotrophin 화학적 특성, 용도, 생산

용도
Gonad-stimulating principle.
일반 설명
Pituitary hormones prepared from the urine of postmenopausalwomen whose ovarian tissue does not respondto gonadotropin are available for medicinal use as theproduct menotropins (Pergonal). The latter has FSH andLH gonadotropin activity in a 1:1 ratio. Menotropins areuseful in the treatment of anovular women whose ovariesrespond to pituitary gonadotropins but who have a gonadotropindeficiency caused by either pituitary or hypothalamusmalfunction. Usually, menotropins are administeredintramuscularly in an initial dose of 75 IU of FSHand 75 IU of LH daily for 9 to 12 days, followed by 10,000IU of chorionic gonadotropin 1 day after the last dose ofmenotropins.
Clinical Use
Menotropins are a natural product that is obtained from the urine of postmenopausal women and then biologically standardized (international units [IU]) for FSH and LH activities in an approximate ratio of 1:1. Menotropins are used in males with primary (hypothalamic) or secondary (pituitary) hypogonadism to stimulate spermatogenesis, providing they have been treated previously with human chorionic gonadotropin (hCG; a peptide hormone of placental origin that has activity very similar to LH) to effect masculinization (increased testosterone inducing ovulation in women who are having difficulty ovulating as a result of either hypothalamic or pituitary hormonal dysfunction. The menotropins are given for 7 to 12 days, and after clinical evaluation (via ultrasound) indicates the presence of a mature follicle, a single dose of hCG is given to simulate the typical LH surge that normally triggers ovulation. Also, women use the combination of menotropins and hCG to promote the development of multiple follicles when they are participating in an IVF program requiring the recruitment of follicles.
부작용
Side effects: Headache, mild stomach pain/bloating, redness/pain at the injection site, breast tenderness, or dizziness may occur.
Serious side effects, including: vaginal bleeding, flu-like symptoms (such as fever, chills, joint pain, muscle ache, tiredness).

Human Menopausal Gonadotrophin 공급 업체

Human Menopausal Gonadotrophin 관련 검색

Send Inquriy