β-Secretase Substrate IV, Fluorogenic - Calbiochem

β-Secretase Substrate IV, Fluorogenic - Calbiochem 화학적 특성, 용도, 생산

• 일반 설명

  A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate (excitation max.: ~350 nm; emission max.: ~490), based on the GVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor Protein. Hydrolysis of the substrate at Leu-Asp bond by β-secretase results in fluorescence enhancement. Reported K_cat/k_m values (min^-1/μM) for pro-mempasin 2 and its proteolytically activated species Leu^28p-mempasin 2 are 0.044 and 0.040, respectively (at pH 4.5, 37°C).

• Biochem/physiol Actions

  Product does not compete with ATP.

β-Secretase Substrate IV, Fluorogenic - Calbiochem 공급 업체

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