PYROQUILON

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H412：장기적 영향에 의해 수생생물에 유해함

• 예방조치문구

  P273：환경으로 배출하지 마시오.

PYROQUILON 화학적 특성, 용도, 생산

• 용도

  Pyroquilon is used for the control of blast (Pyricularia oryzae) in rice.

• 정의

  ChEBI: A pyrroloquinoline that is 1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline in which the hydrogens at position 4 are replaced by an oxo group. A fungicide used to control rice blast, it is not approved wof use within the Eur pean Union.

• 신진 대사 경로

  The fate of pyroquilon in rice and rats has been reported. Given the metabolic stability of cyclic amides, there are few options, other than hydroxylation, open for the metabolism of the compound. Its biotransformation involves initial hydroxylation at three sites in the molecule, followed by ring-opening, dehydration and further oxidation affording a somewhat complex picture. A study in rats revealed most of these metabolites but with some further metabolic degradation. The usual differences in conjugation were seen with mainly glucoside formation in plants and glucuronide and sulfate formation in animals.

• 신진 대사

  Animals: Rapidly metabolized and eliminated via urine and feces. Residues in tissues were generally low, and there was no evidence for accumulation or retention of pyroquilon or its metabolites. Plants: Major metabolites in rice grain were 3,4-dihydro-4-hydroxy-2- oxoquinoline-8-acetic acid and two other acetic acid derivatives. Soil/Environment: DT₅₀ (silty soil) 2, (sandy loam) 18 w. Kd 1.3–42 μg/g soil, little to moderately mobile. Photolysis in water, DT₅₀ 10 d.

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