(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine

(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine 화학적 특성, 용도, 생산

• 개요

  One of two alkaloids isolated from the leaves of Craspidospermum verticilliatum var. petiotare, this base also occurs in the leaves of Crioceras diptadeniij1oris. It yields colourless needles when crystallized from hexane and is laevorotatory with a specific rotation of [α]²⁰_D- 42° (c 1.0, CHC13). The ultraviolet spectrum in EtOH consists of two absorption maxima at 248 and 299 nm. The base has been characterized as the N-methyl derivative with m.p. 138°C and [α]²⁰_D + 60.5° (c 0.9, CHC13). The structure given has been established from chemical degradations and spectroscopic investigations.

• 참고 문헌

  Bruneton, Bouquet, Cave, Phytochem., 13, 1963 (1974)
  Kan-Fan et at., Bull. Soc. Chim. Fr. (12 part 2), 2839 (1974)