Ochrobirine

Ochrobirine 화학적 특성, 용도, 생산

• 개요

  A Corydalis alkaloid, this base is found in C. lutea (L.) D. C., C. ochroleuca Koch and C. sibirica Pers. It forms colourless crystals from MeOH with I mole of solvent, m.p. l38-9°C and has [α] ²¹ + 35.9° (CHCI3). It yields a crystalline acetate, m.p. 177°C and on treatment with Zn-amalgam is converted into an isomeric base with m.p. 238°C. The structure of the alkaloid, deduced from chemical and physical evidence has been confirmed by the synthesis of the optically active form.

• 참고 문헌

  Manske., Can. J. Res., 18B, 75 (1940)
  Total synthesis: Kametani, Hibino, Takano., Chern. Cornrnun., 925 (1971)