이소발레릴조효소a리튬염수화물

이소발레릴조효소a리튬염수화물 화학적 특성, 용도, 생산

• 용도

  Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:
  
  • as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts from G. reessii
  • in high-performance liquid chromatography (HPLC) for the characterization of IV-CoA from lymphocytes
  • as a substrate in isovaleryl-CoA dehydrogenase assay
  
  

• 정의

  ChEBI: A methylbutanoyl-CoA is the S-isovaleryl derivative of coenzyme A.

• 일반 설명

  Isovaleryl coenzyme A, an intermediate of the leucine catabolism. It is synthesized from β-methylbutyric acid by the action of enzyme acyl CoA synthetase. The conversion of isovaleryl-CoA to methylcrotonyl-CoA is catalyzed by the enzyme isovaleryl-CoA dehydrogenase in leucine catabolism pathway. The enzyme isovaleryl-CoA oxidase also calalyzes this conversion in fatty acid β-oxidation pathway.

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