비에타미베린

비에타미베린 화학적 특성, 용도, 생산

• Originator

  Bietamiverine,Shanghai Lansheng Corporation

• Manufacturing Process

  To a solution of 117 g of diethylaminoethanol in 1000 ml of benzene was added a solution of 94.5 g phenylchloroacetic acid in 400 ml benzene (time of addition 1 hour). Then the reaction mixture was refluxed for 2 hours. To the obtained solution was added an aqueous solution of sodium carbonate. Then to the solution which was dried with sodium sulfate was added 85 g of piperidine and the solution was refluxed for 2 hours. The obtained solution was washed with water, dried with sodium sulfate and distilled. Yield of α- phenyl-1-piperidineacetic acid 2-diethylaminoethyl ester 115 g, Kp1 180°C.

• Therapeutic Function

  Spasmolytic

비에타미베린 준비 용품 및 원자재

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