Ｎシアノメチル４（トリフルオロメチル）ニコチンアミド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P501：内容物/容器を．．．に廃棄すること。

Ｎシアノメチル４（トリフルオロメチル）ニコチンアミド 価格

Ｎシアノメチル４（トリフルオロメチル）ニコチンアミド 化学特性,用途語,生産方法

• 外観

  白色〜わずかにうすい灰褐色, 結晶性粉末〜粉末

• 溶解性

  水 5.2(g/l, 20℃)水、エタノール及びアセトンに溶ける。

• 用途

  摂食行動阻害剤アザミウマ目の一部の害虫に対しても効果を示す

• 説明

  Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel K_ir1 (IC₅₀ = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC₅₀s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD₅₀ = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture.

• 使用

  Flonicamid is an novel insecticide with rapid inhibitory effect against aphid feeding.

• 主な応用

  With foliar spray application at the rates of 50-100 g a.i./ha, onicamid exhibits excellent aphicidal activity and also shows good insecticidal activity against other sucking insect pests such as thrips, whiteies, planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees, cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid soil applications also provide control of the foliar pests mentioned above.

• 定義

  Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was assessed through laboratory selection and determining inheritance pattern and cross-resistance potential to five insecticides in house fly, Musca domestica L. Very low to high flonicamid resistance in M. domestica populations was found compared with the susceptible strain (SS).

• 作用机制

  アブラムシ，コナジラミ，ウンカ，ヨコバイなどのヨコバイ亜目害虫の神経系に選択的に作用し，摂食行動（吸汁行動）を阻害して餓死させる

• 合成

  Flonicamid is commercially produced through a multi-step chemical synthesis that begins with the preparation of 4-trifluoromethylnicotinic acid, which serves as the core structural component. This acid is converted into its acid chloride form using reagents like thionyl chloride, enabling it to react with aminoacetonitrile hydrochloride in the presence of a base and a phase-transfer catalyst. The resulting intermediate amide is then treated with aqueous sodium carbonate to yield flonicamid, a compound with high purity and yield.

Ｎシアノメチル４（トリフルオロメチル）ニコチンアミド 生産企業

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Ｎシアノメチル４（トリフルオロメチル）ニコチンアミド スペクトルデータ(¹HNMR)

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