6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 価格

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 化学特性,用途語,生産方法

• 説明

  B-HT 933 is an agonist of α₂-adrenergic receptors (α₂-ARs) with an EC₅₀ value of 0.65 μM for contraction of canine sapheneous veins. It induces concentration-dependent inhibition of the twitch response in rat vas deferens and guinea pig ileum. B-HT 933 induces sedation and reduces motor activity in mice, an effect that is reversed by the α₂-AR antagonist yohimbine . B-HT 933 decreases blood pressure and cardiac output in cats injected with 30 μg/kg intracisternally. It also exhibits antinociceptive effects in mice with ED₅₀ values of 12.5, 20.5, and 6.1 mg/kg for the tail-immersion, tail-pinch, and acetic acid writhing tests, respectively.

• 使用

  B-HT 933 Dihydrochloride is a selective α2-adrenoceptor agonist and has less potent inhibitory effect on the sympathetic vasopressor responses in diabetic rats.

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 生産企業

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36067-72-8, 6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 キーワード