(±)-DOI 塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P271：屋外または換気の良い場所でのみ使用すること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

(±)-DOI 塩酸塩 価格

(±)-DOI 塩酸塩 化学特性,用途語,生産方法

• 一般的な説明

  A Certified Spiking Solution^? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action.

• 生物活性

  Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α .

• Biochem/physiol Actions

  (±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum.

42203-78-1, (±)-DOI 塩酸塩 キーワード