2-(4-メトキシ-α-フェニルベンジルオキシ)-N,N-ジメチルエタンアミン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

2-(4-メトキシ-α-フェニルベンジルオキシ)-N,N-ジメチルエタンアミン 化学特性,用途語,生産方法

• Originator

  Medrylamine,Shanghai Lansheng Corporation

• Manufacturing Process

  A 116 parts by weight of phenyl-p-methoxy-chloromethane (4- methoxybenzhydryl chloride) were added to 500 parts by weight of toluene and to the resulting mixture 65 parts by weight of 2-dimethylaminoethanol was added. Then the entire mixture was refluxed for two hours. The refluxed mixture was cooled and 250 parts by weight of a 10% solution of sodium hydroxide were added. This alkaline mixture was then steam distilled until the distillate was only weakly alkaline, for example a pH 7.5-8.
  The residue of this steam distillation was then mixed with 200 parts by weight of benzene and washed with water until the wash waters were practically neutral. The benzene solution was then evaporated to dryness until the resulting mixture was of constant weight (145 parts). This product was oily and was then dissolved in 3000 parts by weight of dry ether; and treated while being agitated with the theoretically equivalent amount of dry hydrochloric acid dissolved in ether. This product is an oily product, which solidified after standing overnight in an ice box. The ether solution was decanted off and the solidified residue was dissolved in 1500 parts by weight of dioxane, and then precipitated with 3000 parts by weight of ether while being continuously agitated. The resulting solid product was the hydrochloride of 2-(p-methoxy-α-phenylbenzyloxy)-N,N-dimethylethylamine 100 parts by weight of the desired product were obtained corresponding to a yield of 62% and having a melting point of 141°C.

• Therapeutic Function

  Antihistaminic

2-(4-メトキシ-α-フェニルベンジルオキシ)-N,N-ジメチルエタンアミン 上流と下流の製品情報

2-(4-メトキシ-α-フェニルベンジルオキシ)-N,N-ジメチルエタンアミン 生産企業

Global(6)Suppliers

524-99-2, 2-(4-メトキシ-α-フェニルベンジルオキシ)-N,N-ジメチルエタンアミン キーワード