炭酸二ナトリウム·10水和物

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H319：強い眼刺激

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P337+P313：眼の刺激が続く場合：医師の診断/手当てを受けること。

炭酸二ナトリウム·10水和物 価格

炭酸二ナトリウム·10水和物 化学特性,用途語,生産方法

• 外観

  白色の結晶

• 溶解性

  水に可溶 (7.1g/100g水, 0℃ : 48.5g/100g水, 104℃), エタノールに不溶。水に溶けやすく、エタノールにほとんど溶けない。

• 用途

  ガラス原料、写真薬

• 効能

  アルカリ化剤

• 使用上の注意

  風解しやすい。

• 化学的特性

  Sodium carbonate decahydrate is known as sal soda or washing soda. Its chemical formula is Na2CO3.10H2O. Anhydrous sodium carbonate, Na2CO3, is commonly called soda ash. Sodium carbonate is a white, almost white, or colorless inorganic salt, produced as crystalline powder or granules. It is hygroscopic and odorless with an alkaline taste. The decahydrate, NaCO3.10H2O (washing soda) is a translucent efflorescence crystalline solid. It can be used in the preparation of eutectic hydrate salts, which can be used to remove phase change materials for thermal energy storage. It can also be dehydrated to generate cold heat using a chemical heat pump.

• 使用

  Sodium carbonate decahydrate is used as a raw material in various industries like glass, paper making, soap, detergent, textile and leather. It is also used as a food additive. It is also involved as a precipitation agent of carbonate as well as an analytical reagent in laboratories. It plays an important role as strong base and powerful electrolyte. It finds application in metal refining and cement production.

• 調製方法

  Sodium carbonate is produced by the ammonia-soda process, also known as the Solvay process.

• 応用例（製薬）

  Sodium carbonate is used as an alkalizing agent in injectable, ophthalmic, oral, and rectal formulations. In effervescent tablets or granules, sodium carbonate is used in combination with an acid, typically citric acid or tartaric acid. When the tablets or granules come into contact with water, an acid– base reaction occurs in which carbon dioxide gas is produced and the product disintegrates. Raw materials with low moisture contents are required to prevent the early triggering of the effervescent reaction.
  As an alkalizing agent, concentrations of sodium carbonate between 2% and 5% w/w are used in compressed tablet formulations. As an effervescent agent, concentrations of sodium carbonate up to 10% w/w can be used.
  Therapeutically, sodium carbonate is also used as an oral antacid.

• 安全性

  Sodium carbonate is used in injectable, oral, and rectal pharmaceutical formulations. The pure form of sodium carbonate is mildly toxic by ingestion, moderately toxic by inhalation and SC routes, and very toxic by the IP route. It is irritating to the skin and eyes. Dust and vapors of sodium carbonate may irritate mucous membranes, causing coughing and shortness of breath. It also has experimental reproductive effects.
  Sodium carbonate can migrate to food from packaging materials. When used as an excipient or antacid, sodium carbonate is generally regarded as a nontoxic and nonirritating material.
  LD50 (mouse, IP): 0.12 g/kg
  LD50 (mouse, SC): 2.21 g/kg
  LD50 (rat, oral): 4.09 g/kg

• 貯蔵

  Sodium carbonate converts to the monohydrate form when in contact with water and produces heat. It begins to lose carbon dioxide at temperatures above 400℃ and decomposes before boiling. Store in airtight containers.

• 不和合性

  Sodium carbonate decomposes when in contact with acids in the presence of water to produce carbon dioxide and effervescence. It may react violently with aluminum, phosphorous pentoxide, sulfuric acid, fluorine, and lithium.

• 規制状況(Regulatory Status)

  GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections; ophthalmic solution; oral capsules and tablets; rectal suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral (powder for solution for injection) and nonparenteral medicines (oral effervescent tablets, soluble tablets, granules, lozenges, chewing gums) licensed in the UK.
  USP32–NF27 allows either the anhydrous or the monohydrate form.

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