D-エリスロ-スフィンゴシン,N-アセチル-

D-エリスロ-スフィンゴシン,N-アセチル- 価格

D-エリスロ-スフィンゴシン,N-アセチル- 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色, 粉末又は顆粒

• 溶解性

  クロロホルムに溶ける。

• 用途

  情報伝達系の研究、有機合成原料(医薬、農薬、化粧品）。

• 説明

  C2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides. These processes include differentiation of HL-60 cells, induction of apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. C2 ceramide also enhances the expression of COX-2 in human dermal fibroblasts and stimulates the growth of bovine aortic smooth muscle cells. The ability of C2 ceramide to destabilize membranes may be responsible for its inhibition of platelet aggregation.

• 化学的特性

  White Crystalline Solid

• 使用

  A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2

• 生物活性

  A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro .

D-エリスロ-スフィンゴシン,N-アセチル- 生産企業

Global(120)Suppliers

D-エリスロ-スフィンゴシン,N-アセチル- スペクトルデータ(¹HNMR)

3102-57-6, D-エリスロ-スフィンゴシン,N-アセチル- キーワード