ダイレクト ブルー 14

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H350：発がんのおそれ

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

  P405：施錠して保管すること。

  P501：内容物/容器を．．．に廃棄すること。

ダイレクト ブルー 14 価格

MSDS Information

• Direct Blue 14

ダイレクト ブルー 14 化学特性,用途語,生産方法

• 外観

  暗褐色～暗紫褐色, 結晶～粉末及び小塊

• 溶解性

  水に溶ける。

• 解説

  トリパンブルー，C34H24N6Na4O14S4(960.82)．タンパク質に強く結合するアゾ色素．青灰色の粉末．水に可溶，エタノールに不溶．0.01％ 程度の深青色の生理的塩類溶液で細胞を処理すると，膜に傷害のある細胞にはすみやかに侵入して染色するが，健全な細胞は染色しないので，細胞の生死を判定する色素排除試験に用いられる．血流に加えたとき，血清タンパク質との結合物が貪食作用によって細胞内に取り込まれて，青い顆粒を生じることから，尿細管上皮，そのほかの細胞の生体染色に用いられる．また，トリパノゾーマ症の治療に用いられた．

• 用途

  染料

• 用途

  トリパノゾーマ症の治療に用いられた。死細胞染色色素。細胞死の一般的な判定方法として古くから最も多く用いられているものがTrypan Blueを用いた分染法と呼ばれる一種の生体染色法である。

• 化学的特性

  Trypan Blue is a dark Blue crystalline solid or powder that dissolves in water to form a blue solution. It's slightly soluble in soluble fiber yarn and doesn't dissolve in other organic solvents. When mixed with concentrated sulfuric acid, it turns dark greenish-blue, and when diluted, it becomes reddish-blue. With concentrated nitric acid, it creates a brownish-gray solution. In a 10% sulfuric acid solution, its aqueous solution turns red, while with sodium hydroxide, it becomes reddish-purple.
  

• 定義

  ChEBI: Trypan blue is an organosulfonate salt that is the tetrasodium salt of 3,3'-[(3,3'-dimethylbiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid). It has a role as a histological dye, a fluorochrome and a carcinogenic agent. It is an organosulfonate salt and an organic sodium salt. It contains a trypan blue(4-).

• 製造方法

  3,3′-Dimethylbenzidine double nitriding, in alkaline conditions and 4-Amino-5-hydroxynaphthalene-2,7-disulfonic acid(2 Moore) coupled.

• 一般的な説明

  Bluish-gray to dark blue powder.

• 空気と水の反応

  Azo dyes can be explosive when suspended in air at specific concentrations. Slightly soluble in water.

• 反応プロフィール

  Direct Blue 14 is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Direct Blue 14 is incompatible with strong oxidizing agents and strong acids.

• 健康ハザード

  ACUTE/CHRONIC HAZARDS: Direct Blue 14 may cause irritation and may be absorbed through the skin. It is a positive animal carcinogen. When heated to decomposition Direct Blue 14 emits very toxic fumes of nitrogen oxides, sulfur oxides, carbon monoxide and carbon dioxide.

• 火災危険

  Flash point data for Direct Blue 14 are not available; however, Direct Blue 14 is probably combustible.

• 安全性プロファイル

  Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal, intravenous, and subcutaneous routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx NazO, and SOx

• 職業ばく露

  Used in dyeing textiles; leather and paper; as a biological stain.

• 輸送方法

  UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 dyes, solid, toxic, n.o.s. or dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

• 不和合性

  Dust may form explosive mixture with air. Trypan Blue is incompatible with strong oxidizing agents. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Azo compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acylhalides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combinations can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Trypan Blue is sensitive to prolonged exposure to heat.

• 廃棄物の処理

  Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

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