4-ブトキシメチル-2-メトキシフェノール

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H317：アレルギー性皮膚反応を起こすおそれ

  H319：強い眼刺激

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P272：汚染された作業衣は作業場から出さないこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P333+P313：皮膚刺激または発疹が生じた場合：医師の診断/手当てを 受けること。

  P337+P313：眼の刺激が続く場合：医師の診断/手当てを受けること。

  P501：内容物/容器を．．．に廃棄すること。

4-ブトキシメチル-2-メトキシフェノール 価格

4-ブトキシメチル-2-メトキシフェノール 化学特性,用途語,生産方法

• 外観

  無色～淡黄色、液体

• 定義

  本品は、バニリルアルコールのブチルエーテルである。

• 用途

  香料材料、有機合成原料。

• 化粧品の成分用途

  ヘアコンディショニング剤、口腔ケア剤、皮膚コンディショニング剤、香料

• 説明

  Vanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.

• 化学的特性

  Vanillyl butyl ether has a weak, vanillic, acidic odor.

• 使用

  Vanillyl butyl ether is a compound hypothesized to have warming and vasodilation mechanisms when applied on the skin as a cream.

• 一般的な説明

  Vanillyl butyl ether is an alkoxy-substituted benzyl derivative mainly used as a flavoring agent.

• 副作用

  Vanilloids contain vanillyl groups that bind to the transient receptor potential type V1 channel (Vanilloid receptor-1, TRPV1) that respond to noxious stimuli such as high temperatures and acidic pH. This causes neurons to release glutamate, adenosine triphosphate (ATP) and a variety of neuropeptides, resulting in the warming sensation. Vanillyl butyl ether causes serious eye irritation and may cause an allergic skin reaction.

• 安全性

  Vanillyl butyl ether (VBE) is a weak skin sensitizer, which is a substance whose chemical structure indicates that it is expected to react with skin proteins, with a NESIL value of 3500 μg/cm2. VBE is not genotoxic, phototoxic or photosensitizing. In addition, VBE is not persistent, bioaccumulative and toxic (PBT) according to IFRA environmental criteria, and its risk quotient is less than 1 based on its current use in Europe and North America (i.e. PEC/PNEC). The local respiratory toxicity endpoint was evaluated using the Threshold of Toxicological Concern (TTC) for Cramer Class III materials, and exposure to VBE was below the TTC (0.47 mg/day)^[1].

• 合成

  At present, the synthesis of vanillyl butyl ether is mainly obtained by dehydrating and condensing vanillyl alcohol and n-butyl alcohol under an acid catalyst. However, the yield of the method is low mainly because water generated by the reaction can inhibit the etherification reaction. The common acid catalyst such as AlCl is used3、FeCl3It is easy to hydrolyze in the presence of water and lose its catalytic action. A new synthesis method comprises the following steps: dissolving vanillin in a solvent, adding a metal complex hydride and an alkylating reagent after uniformly stirring, reacting for 3-4 hours at 30-40 ℃ to obtain a vanillin alcohol ether solution, and separating and purifying the vanillin alcohol ether solution to obtain vanillin alcohol ether.

4-ブトキシメチル-2-メトキシフェノール 生産企業

Global(332)Suppliers

4-ブトキシメチル-2-メトキシフェノール スペクトルデータ(¹HNMR)

82654-98-6, 4-ブトキシメチル-2-メトキシフェノール キーワード