アクリル酸6-[4-(4-シアノフェノキシカルボニル)フェノキシ]ヘキシル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

アクリル酸6-[4-(4-シアノフェノキシカルボニル)フェノキシ]ヘキシル 化学特性,用途語,生産方法

• 使用

  4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.

• 合成

  
  The target monomer was prepared by firstly converting the acid into the corresponding acid chloride, then condensing this withp-cyanophenol. The acid (17.32 g, 0.059 mol) was stirred with thionyl chloride (35.7 g, 0.3 mol) in the presence of DMF (2 drops) and 2,6-di-tert-butyl-4-methyl phenol (4.4 g, 0.02 mol). After ca. 25 min, by which time solution was achieved, the excess thionyl chloride was removed by rotary evaporation and high vacuum (1-2 h). The acid chloride residue was dis- solved in anhydrous chloroform (30 mL), then added slowly dropwise into a stirred solution of p-cyanophenol (7.03 g, 0.059 mol) and triethylamine (6.07 g, 0.06 mol) in chloroform (20 mL) at 0??C. After the addition the mixture was stirred at room temperature for 24 h and then chloroform (200 mL) added. This solution was washed with water (50 mL) followed by 2 N sodium hydroxide solution (3 x 50 mL) and water (2 x 50 mL). The organic layer was dried (MgSO,), evaporated, then subjected to flash chromatography, using dichloro- methane as both the solvent and the eluant. The monomer was finally recrystallized from isopropanol and shown to be pure by tlc. Yield: 16 g, 69%.

アクリル酸6-[4-(4-シアノフェノキシカルボニル)フェノキシ]ヘキシル 上流と下流の製品情報

アクリル酸6-[4-(4-シアノフェノキシカルボニル)フェノキシ]ヘキシル 生産企業

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