α-シクロヘキシルベンゼン酢酸2-(ジエチルアミノ)エチル

α-シクロヘキシルベンゼン酢酸2-(ジエチルアミノ)エチル 化学特性,用途語,生産方法

• Originator

  Trasentine A,Ciba

• Manufacturing Process

  17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in 200 parts of acetic acid and hydrogenated over platinum catalyst. After the calculated volume of hydrogen was passed, the catalyst was filtered off and the solvent was removed to dryness. Ether, water and a potassium carbonate solution were added to the remaining oil and were thoroughly shaken. The ether layer was washed with water and dried over potassium carbonate. The solvent was removed, the remaining oil was distilled in vacuum to give 2- (diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
  In practice it is usually used as hydrochloride.

• Therapeutic Function

  Spasmolytic

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