1,3-ジメチル-5-フルオロウラシル

1,3-ジメチル-5-フルオロウラシル 価格

1,3-ジメチル-5-フルオロウラシル 化学特性,用途語,生産方法

• 使用

  5-Fluoro-1,3-dimethyluracil may be used as starting material in the following processes:
  
  • Regioselective synthesis of tetrahydronaphthocyclobuta[1,2-d]pyrimidinediones.
  • To synthesize 5-bis(ethoxycarbonyl)methyl-1,3-dimethyluracil.
  • To synthesize new highly conjugated propenylidene derivatives via aromatic Paterno-Buchi type cycloaddition with 1-methoxynaphthalene.

• Synthesis Reference(s)

  Tetrahedron, 46, p. 3093, 1990 DOI: 10.1016/S0040-4020(01)88400-3

• 一般的な説明

  Oxidation of 5-fluoro-1,3-dimethyluracil (5-FDMU) with m-chloroperbenzoic acid has been described. It is reported as antineoplastic drug. On photoirradiation, 5-fluoro-1,3-dimethyluracil yields the trans-anti cyclobutane dimer and the cis-syn cyclobutane dimer. UV irradiation of 5-FDMU and naphthalene in a protic medium affords 5-(1-naphthyl)uracil, while in aprotic media it undergoes stereoselective 1,4-cycloaddition reaction to give a barrelene derivative. The thermochemical parameters of 5-FDMU has been determined. It reacts with substituted benzenes in the presence of trifluoroacetic acid to generate 5-aryl-1,3-dimethyluracils via photosubstitution.

1,3-ジメチル-5-フルオロウラシル 生産企業

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1,3-ジメチル-5-フルオロウラシル スペクトルデータ(FT-IR、IR、Raman)

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