ブナフチン

ブナフチン 化学特性,用途語,生産方法

• 効能

  抗不整脈薬, カリウムチャネル遮断薬

• Originator

  Bunaftine,Malesci

• Manufacturing Process

  Into a solution containing α-naphthoic acid chloride in benzene with agitation and cooling for 0.5 h a benzene solution of N,N-diethylamine-ethyl-N'-(nbutyl) amine is dropped. As the dropping is ended, the solution is kept under agitation in a water bath for 3 h.
  After cooling the benzene solution is extracted with 10% hydrochloric acid; then the aqueous solution is saturated with potassium carbonate. The separated oil is extracted with ether and, after drying on sodium sulfate, the solvent is removed and the residue is vacuum distilled. So the N-(2- diethylamino-ethyl)-N-(n-butyl)-1-naphthalenecarboxamide, boiling point 178°C/0.1 mm/Hg.

• Therapeutic Function

  Antiarrhythmic

ブナフチン 上流と下流の製品情報

ブナフチン 生産企業

Global(18)Suppliers

32421-46-8, ブナフチン キーワード