Ferrous Bisglycinate

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H312：皮膚に接触すると有害

  H332：吸入すると有害

  H400：水生生物に強い毒性

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P271：屋外または換気の良い場所でのみ使用すること。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P304+P340：吸入した場合：空気の新鮮な場所に移し、呼吸しやすい 姿勢で休息させること。

  P312：気分が悪い時は医師に連絡すること。

  P322：特別な処置が必要である（このラベルの．．． を見よ）。

  P330：口をすすぐこと。

  P363：汚染された衣類を再使用す場合には洗濯をすること。

  P391：漏出物を回収すること。

  P501：内容物/容器を．．．に廃棄すること。

Ferrous Bisglycinate 化学特性,用途語,生産方法

• 使用

  Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine.
  Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

• 食品添加物

  Amino acid chelates are recommended for milk and beverage products. Ferrous bisglycinate has Generally Recognized as Safe (GRAS) status but is relatively expensive and readily promotes fat oxidation in cereal foods unless an anti-oxidant is added, and causes undesirable color reactions in some foods. Four non controlled efficacy studies with ferrous bisglycinate fortified foods have reported a marked decrease in the prevalence of anemia or iron deficiency anemia in children or adolescents. Three studies made in Brazil reported good efficacy in fortified liquid milk, sweetened bread rolls and a whey based beverage, and a fourth study in Saudi Arabia reported good efficacy in an iron fortified flavored milk drink. Recently, fer- rous bisglycinate fortified bread made from high extraction flour resulted in small but significant increases in both hemoglobin and serum ferritin when fed in a randomized controlled design to South African schoolchildren. A longer feeding period with higher iron concentrations would probably have given more impressive results. The influence of ferrous bisglycinate on stored flour was not investigated in this study. The main disadvantage of ferrous bisglycinate is its high cost. A recent cost analysis showed the cost of ferrous bisglycinate, taking bioavailability into account, to be 7–18 times that of ferrous sulfate.

• 副作用

  Ferrous Bisglycinate is a novel amino acid iron chelate that is more bioavailable and has fewer gastrointestinal (GI) adverse effects than iron salts. Adverse effects such as constipation, diarrhoea, stomach cramps or upset stomach may occur with Ferrous Bisglycinate. However, usually these effects are temporary and can recover on their own. Iron may cause your faeces to become darker; this effect is harmless. In addition, in the event of a severe allergic reaction to the drug, you need to stop taking it immediately and contact your doctor.

• 合成

  600kg water is added in 1500L reactor, 150kg glycine, 1.5kg carbonyl iron dust, and heating is added under agitation. Stir for 20 minutes to 65 DEG C, then add 550kg ferrous sulfate heptahydrates, 37.5kg maltodextrins, 0.3kg silica, 78 DEG C reaction 30 minutes, reaction complete. Reaction solution sieves heat filtering with 100 mesh stainless sheets of steel, and the filtrate is dried with a pressure spray drying tower, obtained To yellowish-brown green powder Ferrous Bisglycinate 490kg.

• 参考文献

  [1] Adelia C Bovell-Benjamin, Lindsay H Allen, Fernando E Viteri. “Iron absorption from ferrous bisglycinate and ferric trisglycinate in whole maize is regulated by iron status123.” American Journal of Clinical Nutrition 71 6 (2000): Pages 1503-1509.

Ferrous Bisglycinate 生産企業

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20150-34-9, Ferrous Bisglycinate キーワード