ベンズガランタミングルコン酸塩

ベンズガランタミングルコン酸塩 化学特性,用途語,生産方法

• 効能

  認知症治療薬, アセチルコリンエステラーゼ阻害薬

• 説明

  Benzgalantamine is a prodrug of galantamine. Gastrointestinal adverse effects are the most frequently reported side effects in patients undergoing treatment with cholinesterase inhibitors, including galantamine, and are often a reason for treatment discontinuation. As a prodrug, benzagalantamine remains inert as it passes through the stomach, thereby avoiding many of the gastrointestinal effects associated with peripheral cholinesterase inhibition.
  Benzgalantamine was approved by the FDA in July 2024 for the treatment of mild-to-moderate dementia in Alzheimer's patients.

• 化学的特性

  Benzgalantamine gluconate is derived from the dried flowers of Lycoris radiata (family Amaryllidaceae, formerly classified as Liliaceae/Lycoraceae). It occurs as a white or off-white crystalline powder, odorless with a bitter taste. It is soluble in water, slightly soluble in ethanol, almost insoluble in acetone, trichloromethane and ether.

ベンズガランタミングルコン酸塩 生産企業

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