3-(1-ナフトイル)インドール

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

3-(1-ナフトイル)インドール 価格

3-(1-ナフトイル)インドール 化学特性,用途語,生産方法

• 説明

  3-(1-Naphthoyl)indole is a synthetic cannabinoid that is structurally similar to THC. It has been detected in human urine, plasma and autopsy samples by high-resolution mass spectrometry. It has been found to be hydroxylated into a number of metabolites including carboxy-3-(1-naphthoyl)indole, which may account for some of the psychoactive effects.

• 化学的特性

  Off-White to Light Pink Solid.

• 使用

  Metabolite of JWH-018 (P283650).

• 合成

  To a cooled solution of indole (5.85g, 50mmol) in ether (50ml) under nitrogen was added slowly a solution of methylmagnesium bromide (3M) in ether (17.5ml). After addition, the reaction mixture was warmed up to room temperature and stirred for 2h at room temperature. Then, the mixture was cooled down again to 0°C and added slowly, stirring a solution of 1-naphthoylchloride (9.5g, 50mmol) in ether (50ml). The resulting mixture was warmed up to room temperature and stirred for 2h at room temperature, followed by a slow addition of saturated ammonium chloride solution (375ml). The mixture was then stirred overnight at room temperature. A white solid was formed, filtered, washed by ether, and dried under a high vacuum to give 3-(1-Naphthoyl)indole (12.3g, 91%).
  

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