(3α,6α,7R,8S,9R,10α,11α)-デンドロバン-12-オン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

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(3α,6α,7R,8S,9R,10α,11α)-デンドロバン-12-オン 化学特性,用途語,生産方法

• 説明

  Dendrobine is a sesquiterpenoid that has been found in D. nobile and has anticancer activity. It decreases viability of A549 cells when used at concentrations ranging from 2.5 to 15 μg/ml. It induces apoptosis in A549 cells when used at concentrations ranging from 1 to 10 μg/ml, as well as increases JNK phosphorylation and sensitizes A549 cells to cisplatin at 10 μg/ml. Dendrobine (50 mg/kg per day) reduces tumor growth in an A549 mouse xenograft model with an additive effect when used in combination with cisplatin.

• 使用

  Dendrobine is an alkaloid isolated from Dendrobium nobile and is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord.

(3α,6α,7R,8S,9R,10α,11α)-デンドロバン-12-オン 生産企業

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2115-91-5, (3α,6α,7R,8S,9R,10α,11α)-デンドロバン-12-オン キーワード