1-オレオイルリゾホスファチジン酸 (ナトリウム塩)

1-オレオイルリゾホスファチジン酸 (ナトリウム塩) 価格

1-オレオイルリゾホスファチジン酸 (ナトリウム塩) 化学特性,用途語,生産方法

• 使用

  Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.

• 一般的な説明

  Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.

• Biochem/physiol Actions

  Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.

1-オレオイルリゾホスファチジン酸 (ナトリウム塩) 生産企業

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