クレゾールレッド

化学名:クレゾールレッド

CAS番号.1733-12-6

英語名:Cresol Red

CBNumberCB4376563

MFC21H18O5S

MW382.43

别名

クレゾールレッド (0.1%, 約20%エタノール溶液)

クレゾールスルホフタレイン

o-クレゾールスルホンフタレイン

クレゾールレッド物理性質

融点	290 °C
沸点	479.59°C (rough estimate)
比重(密度)	0.998 g/cm3
屈折率	1.5300 (estimate)
貯蔵温度	Store at +5°C to +30°C.
溶解性	溶解度水にやや溶けにくい。エタノールに可溶
外見	粉
酸解離定数(Pka)	1.0(at 25℃)
色	ダークグリーンまたはブラウンレッド
酸塩基指示薬変色域(pH)	7.2(YELLOW)--8.8(PURPLISH RED)
PH	7.2～8.8
水溶解度	溶ける
極大吸収波長 (λmax)	570nm, 367nm, 432nm
Merck	14,2578
BRN	343399
主な用途	Display device, optical sensors, combustion gas detection system, inks, correction fluid, diapers, toothpaste, identifying fresh and stale rice, food storage, determine glucose in dialysis solution, monitor metabolic activity of microorganisms, detect bacterialinfection, psychoactive drugs, dental impression material
InChIKey	ASMGMVUGPNODGX-UHFFFAOYSA-N
EPAの化学物質情報	Cresol Red (1733-12-6)

安全性情報

主な危険性	Xi,Xn,F
Rフレーズ	36/37/38-20/21/22-11
Sフレーズ	24/25-36-26-16
RIDADR	UN1170 - class 3 - PG 3 - Ethanol, solution
WGK Germany	3
TSCA	Yes
HSコード	29349990
毒性	A potent lacrimator which is chemically stable and retains its irritancy in water and so can be used in liquid jets in personnel control. In addition to lacrimation, it causes eye pain, blepharospasm, eyelid swelling, irritation of the conjunctiva, a rise in intraocular pressure, and erythema of the skin. Because it can be used in water, its use is less affected by changes in climatic conditions. It is a more potent lacrimator than CS but it is less potent in lethality than CS.
安衛法	57,57-2

危険有害性情報のコード(GHS)

外観
赤色～緑褐色, 結晶性粉末～粉末
溶解性
エタノールにやや溶けにくく、水に溶けにくい。水酸化ナトリウム溶液に溶ける。
用途
酸塩基指示薬 : 変色域が二つある。pH0.4～2.2で赤色から黄色に、pH7.2～8.8で黄色から赤色に変わる。
使用上の注意
アルゴン封入
化学的特性
Dark green or brown-red powder
使用
Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.
定義
ChEBI: A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups.
変色範囲
黄7.2～8.8赤
純化方法
Crystallise it from glacial acetic acid. Dry it in air. Dissolve it in aqueous 5% NaHCO3 solution and precipitate it from a hot solution by dropwise addition of aqueous HCl. Repeat the procedure till the UVmax does not increase. [Beilstein 19 IV 1133.]