レニン基質, ヒト

レニン基質, ヒト 価格

レニン基質, ヒト 化学特性,用途語,生産方法

• 生物学の機能

  Human plasma contains a glycoprotein called angiotensinogen, which serves as the only known substrate for renin. Angiotensinogen must undergo proteolysis before active portions of the protein are sufficiently unmasked to exert biological effects. Angiotensinogen is synthesized in many organs, including the liver, brain, kidney, and fat. Its gene transcription and plasma concentrations increase following treatment with adrenocorticotropic hormone (ACTH), glucocorticoids, thyroid hormone, and estrogens, as well as during pregnancy and inflammation and after nephrectomy. Angiotensinogen also has been found in large quantities in cerebrospinal and amniotic fluid. Mutations in the angiotensinogen gene have been reported to be linked to human hypertension.

レニン基質, ヒト 生産企業

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