リファミド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H319：強い眼刺激

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

リファミド 化学特性,用途語,生産方法

• 効能

  抗生物質

• 使用

  Antibacterial.

• 応用例（製薬）

  The diethyl amide of rifamycin B, formulated as the sodium salt for parenteral administration. It exhibits high activity against Gram-positive organisms and M. tuberculosis typical of the group. MICs for Gram-negative bacilli are of the order of 20–50 mg/L.
  It is absorbed orally and is rapidly eliminated through the bile, achieving concentrations sufficient to inhibit Gramnegative bacilli. In contrast to rifampicin, it can be administered as the sodium salt by intramuscular injection. A dose of 150 mg produces mean plasma levels of about 1 mg/L. The plasma halflife is about 2 h. The same dosage produces concentrations over 1 g/L in bile and c. 40 mg/L in the gallbladder wall.
  Toxicity and side effects are similar to those of other rifamycins. It has been used in staphylococcal infections and infections of the biliary tract. It is unsuitable for the treatment of tuberculosis because of insufficient distribution to the tissues.

リファミド 生産企業

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