3-ニトロソチアゾリジン

3-ニトロソチアゾリジン 化学特性,用途語,生産方法

• 安全性プロファイル

  Moderately toxic by ingestion. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of NOx and SOx.

• 代謝経路

  N-Nitroso-1,3-thiazolidine administered by gavage to rats is excreted mostly in the urine with a small amount in respired air. The major metabolite in the urine is 2-hydroxy-1,3-thiazolidine, and minor quantities of the isomers 4- and 5-hydroxy-1,3- thiazolidines are detected. The presence of hydroxy-1,3-thiazolidine indicates that a-hydroxylation and denitrosation are major metabolic pathways of N-nitroso-1,3-thiazolidine.

3-ニトロソチアゾリジン 生産企業

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