ミクロノマイシン

ミクロノマイシン 化学特性,用途語,生産方法

• 効能

  抗生物質, タンパク質合成阻害薬

• 説明

  Micronomicin, formerly called sagamicin, was found in the culture broth of Micromonospora sagamiensis var. nonreducans by Kyowa Hakko Kogyo Company and Abbott Laboratories in 1974. The compound is identical with one of the minor components contained in gentamicin, gentamicin C2b, but it is produced as a single component. Its amino group at the 6 -position is methylated and is not subject to the enzymatic acetylation caused by resistant bacteria, including Pseudomonas aeruginosa. Micronomicin is less toxic than gentamicin to the renal and aural systems.

• 使用

  Gentamicin C2b (micronomicin) is a trisaccharide pentaaminoglycoside antibiotic belonging to the gentamicin class. Gentamicin C2b was isolated from Micromonospora sagamiensis var. nonreductans by researchers at Kyowa Hakko Kogyo in 1974. Gentamicin C2b has broad activity against Gram positive and Gram negative bacteria. More recently, gentamicin C2b has been shown to induce neuromuscular blockage.

• 抗菌性

  Antibacterial and pharmacokinetic properties are similar to those of its precursor gentamicin C1a but it is more resistant to AAC(6′). Dosage is similar to that for gentamicin, and should be controlled by blood level determinations. It is available in Japan.

ミクロノマイシン 上流と下流の製品情報

ミクロノマイシン 生産企業

Global(42)Suppliers

ミクロノマイシン スペクトルデータ(¹HNMR)

52093-21-7, ミクロノマイシン キーワード