MK-0677 化学構造式

MK-0677

化学名:MK-0677

CAS番号.159634-47-6

英語名:MK-677

CBNumberCB31178916

MFC27H36N4O5S

MW528.66

MOL File159634-47-6.mol

别名

MK-0677

2-アミノ-N-[(R)-2-[[1,2-ジヒドロ-1-(メチルスルホニル)スピロ[3H-インドール-3,4′-ピペリジン]]-1′-イル]-2-オキソ-1-[(ベンジルオキシ)メチル]エチル]-2-メチルプロパンアミド

2-アミノ-2-メチル-N-[(R)-2-(ベンジルオキシ)-1-[[1,2-ジヒドロ-1-(メチルスルホニル)スピロ[3H-インドール-3,4′-ピペリジン]-1′-イル]カルボニル]エチル]プロパンアミド

MK-0677物理性質

比重(密度)	1.32
酸解離定数(Pka)	15.73±0.46(Predicted)
InChIKey	UMUPQWIGCOZEOY-JOCHJYFZSA-N
SMILES	C(N[C@H](COCC1=CC=CC=C1)C(N1CCC2(CC1)C1=C(N(S(C)(=O)=O)C2)C=CC=C1)=O)(=O)C(N)(C)C

危険有害性情報のコード(GHS)

MK-0677 化学特性,用途語,生産方法

説明
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191)is a non-peptidic, potent, long acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.
It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
使用
Growth hormone releasing factor.
利点
The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.
安全性
Ibutamoren is a muscle building anabolic compound. It's considered safe if you don't have high blood glucose level and if you don't suffer from congestive heart failure. It's considered a boon for anti aging and it's a life longevity material. It's considered to be more beneficial than to be harmful. The optimal dose for body building is to take 25mg at bedtime for four to six weeks. It is a water retaining compound so beware of bloating.

MK-0677 上流と下流の製品情報

MK-0677 生産企業

MK-0677 スペクトルデータ(¹HNMR)

Send Inquriy

MK-0677

危険有害性情報のコード(GHS)

MK-0677 化学特性,用途語,生産方法

MK-0677 上流と下流の製品情報

MK-0677 生産企業

MK-0677 スペクトルデータ(1HNMR)

MK-0677 スペクトルデータ(¹HNMR)