3a,4,7,7a-テトラヒドロ-5-(ヒドロキシフェニル-2-ピリジニルメチル)-8-(フェニル-2-ピリジニルメチレン)-4,7-メタノ-1H-イソインドール-1,3(2H)-ジオン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P330：口をすすぐこと。

  P501：内容物/容器を．．．に廃棄すること。

3a,4,7,7a-テトラヒドロ-5-(ヒドロキシフェニル-2-ピリジニルメチル)-8-(フェニル-2-ピリジニルメチレン)-4,7-メタノ-1H-イソインドール-1,3(2H)-ジオン 化学特性,用途語,生産方法

• 説明

  Norbormide was first introduced on the market in 1964 as a selective raticide, but does not have a current registration for commercial use in the European Union or North America. Current use as a pesticide is minimal to nonexistent worldwide. This compound’s toxicity is highly specific for rats.

• 化学的特性

  White solid. Insoluble in water; soluble in dilute acids.

• 使用

  Norbormide is used as a rodenticide. It acts as a vasoconstrictor and calcium channel blocker, but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.

• 定義

  A rodenticide specific for rats, supposedly nontoxic to other animals or to humans .

• 一般的な説明

  Colorless to off-white crystalline powder. Used as a selective rat poison.

• 反応プロフィール

  When heated to decomposition, NORBORMIDE emits toxic fumes of nitrogen oxides. Avoid alkalis. [EPA, 1998].

• 危険性

  Toxic by ingestion.

• 健康ハザード

  Moderately to highly toxic to humans. Probable human lethal dose is 50 to 500 mg/kg, or 1 teaspoon to 1 pint for a 150 lb. person.

• 火災危険

  When heated to decomposition, NORBORMIDE emits toxic fumes of nitrogen oxides. Avoid alkalies.

• 安全性プロファイル

  Poison by ingestion andintravenous routes. A rodenticide. When heated todecomposition it emits toxic fumes of NOx.

• 職業ばく露

  This material is used as a selective, fast acting rat poison.

• 環境運命予測

  Because of its use as a rodenticide, norbormide may have entered the environment, particularly as a soil contaminant. The vapor pressure for norbormide is estimated to be 4.3 ×10^-22 mmHg at 25 ℃, while Henry’s constant is 2.7 × 10^-23 atmm³ mol^-1. Therefore, volatilization from wet or dry soil is not likely to occur. If present in contaminated soil, norbormide may be transported in the air and undergo wet or dry deposition. Also, with a Koc of 2000, there would be some minor soil mobility. The high Koc coupled with a bioconcentration factor (BCF) of 290 predicts that norbormide contaminating aquatic systems would adsorb to suspended solids or sediments and would bioconcentrate.

• 輸送方法

  UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

• 不和合性

  Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).

• 廃棄物の処理

  Small amounts may be treated with alkali, then landfilled. Large amounts should be incinerated . In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

3a,4,7,7a-テトラヒドロ-5-(ヒドロキシフェニル-2-ピリジニルメチル)-8-(フェニル-2-ピリジニルメチレン)-4,7-メタノ-1H-イソインドール-1,3(2H)-ジオン 生産企業

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