2-methyloxan-4-one

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P260：粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

2-methyloxan-4-one 価格

2-methyloxan-4-one 化学特性,用途語,生産方法

• 製造方法

  A solution of (2S)-2-methyltetrahydro-2H-pyran-4-ol (27.3 g, 235 mmol) in acetone (980 mL) was cooled in an ice bath and treated drop-wise with Jones reagent (2.5 M, 103 mL, 258 mmol). The reaction mixture was stirred for 10 minutes at 0 °C and then warmed to room temperature. After 30 minutes, the mixture was cooled to 0 °C. 2-Propanol (18 mL, 240 mmol) was added and stirred for 30 minutes. After the mixture had been concentrated in vacuo, the residue was partitioned between water and dichloromethane. The aqueous layer was extracted 3 times with dichloromethane, and the combined organic layers were dried over magnesium sulfate, filtered, and concentrated under reduced pressure to provide the product 2-methyloxan-4-one.
  

• Synthesis Reference(s)

  The Journal of Organic Chemistry, 59, p. 3494, 1994 DOI: 10.1021/jo00091a048

• 生物活性

  2-methyloxan-4-one has been shown to affect cell function and signal transduction in various cell types. It has been reported to inhibit the growth of cancer cells and induce apoptosis, or programmed cell death. It has also been shown to inhibit the production of inflammatory cytokines and reduce inflammation in animal models. However, the potential therapeutic and toxic effects of 2-methyloxan-4-one in humans are not well studied and require further investigation.

2-methyloxan-4-one 上流と下流の製品情報

2-methyloxan-4-one 生産企業

Global(92)Suppliers

2-methyloxan-4-one スペクトルデータ(¹HNMR)

1193-20-0, 2-methyloxan-4-one キーワード