2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド

2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド 価格

2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド 化学特性,用途語,生産方法

• 使用

  PEPA is an allosteric potentiator of AMPA desensitization.

• 生物活性

  Novel allosteric potentiator of AMPA receptor desensitization. Slows the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by glutamate with subunit (GluR3/4 > GluR1) and splice variant (flop > flip) selectivity. Ameliorates post-ischemic memory impairment in rats following i.v. administration.

• Biochem/physiol Actions

  2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.

2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド 生産企業

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2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド スペクトルデータ(¹HNMR)

141286-78-4, 2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド キーワード