フタル酸ジイソデシル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H319：強い眼刺激

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P321：特別な処置が必要である（このラベルの．．． を見よ）。

  P332+P313：皮膚刺激が生じた場合：医師の診断/手当てを受けるこ と。

  P362：汚染された衣類を脱ぎ、再使用す場合には洗濯をすること。

フタル酸ジイソデシル 価格

フタル酸ジイソデシル 化学特性,用途語,生産方法

• 化学的特性

  The empirical formula of diisodecyl phthalate (DIDP) is C28H46O4. The structural formula of DIDP varies because the iso-alcohols used in the manufacture contain several isomers. DIDPis insoluble in water, but it is soluble in organic solvents.

• 使用

  It is a high-molecular-weight, general-purpose plasticizer that is added to polyvinyl chloride to impart flexibility.

• 調製方法

  DIDP is manufactured by the esterification of phthalic anhydride with isodecyl alcohol in the presence of a catalyst.

• 定義

  ChEBI: Diisodecyl phthalate is a phthalate ester and a diester. Used as plasticizer for polyvinyl chloride in calendered film, coated fabrics, building wire jackets, wire and cable extrusion, and other applications.

• 発がん性

  A 2-year bioassay was conducted in which DIDP was administered in the diet at concentrations of 400, 2000, and 8000 ppm to F344 rats. Rats of both sexes exhibited significant decreases in overall survival and body weights and increases in the relative weights of kidneys and liver with 8000 ppm of DIDP. No treatment-related neoplastic lesions were observed in the internal organs, including the liver. In addition, measurement of catalase enzyme activity, a marker for cell peroxisome proliferating activity, suggests that DIDP can induce peroxisome proliferation at an early stage (12 weeks of treatment) but fails to maintain the catalase-inducing potential by 32 weeks of treatment. An increased incidence of MNCL was observed in this study, butMNCLis a common neoplasm in F344 rats; the observed increased incidence is likely to be a species-specific effect with little or no relevance to humans. Therefore, DIDP was not considered to be carcinogenic at doses up to 8000 ppm in rats.

フタル酸ジイソデシル 生産企業

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