アペリン-13 (ヒト, ウシ, マウス, ラット)

アペリン-13 (ヒト, ウシ, マウス, ラット) 価格

アペリン-13 (ヒト, ウシ, マウス, ラット) 化学特性,用途語,生産方法

• 使用

  The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM (the EC50 values for apelin-17 and apelin-36 are 2.5 and 20 nM, respectively). It acts primarily in the periphery and central nervous system, playing important roles in regulating cardiovascular function, fluid homeostasis, hypertension, and insulin sensitivity. Unlike apelin-36, apelin-13 poorly blocks the entry of human immunodeficiency virus into cells.

• 一般的な説明

  Apelin is a regulatory peptide and a ligand of the APJ receptor. It is a member of the G protein-coupled receptor family. Apelin and APJ are broadly dispersed in the body.

• Biochem/physiol Actions

  Apelin plays physiological roles in the cytoprotection of many internal organs. It is used to treat insulin resistance and hypertension, but it may also can act as a negative factor. Apelin also regulates cardiovascular diseases.

アペリン-13 (ヒト, ウシ, マウス, ラット) 生産企業

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アペリン-13 (ヒト, ウシ, マウス, ラット) スペクトルデータ(MS)

217082-58-1, アペリン-13 (ヒト, ウシ, マウス, ラット) キーワード