3-ブチリデンフタリド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P330：口をすすぐこと。

3-ブチリデンフタリド 価格

3-ブチリデンフタリド 化学特性,用途語,生産方法

• 用途

  有機薄膜光電変換素子，熱電変換素子

• 化学的特性

  3-Butylidenephthalide has a pervasive warm spicy aroma.

• 天然物の起源

  Reported as occurring naturally in the fruits and roots of Ligusticum acutilobum and lovage (Levisticum officinale) seeds, roots and leaves.

• 使用

  3-Butylidenephthalide is a phthalide derivative useful for control of sensation disorder and olfaction disorder.

• 定義

  ChEBI: A gamma-lactone that is phthalide substituted by a butylidene group at position 3. Isolated from Ligusticum porteri, it exhibits hypoglycemic activity.

• 一般的な説明

  3-Butylidenephthalide is a bioactive phthalide compound of Chuanxiong rhizoma, a Chinese herbal medicine used for treating headache obtained from the root of Ligusticum chuanxiong Hort.

• 化学性质

  クレイを架橋点とした機/有機のハイブリッドゲル

• 細胞毒性(Cytotoxicity)

  The anti-proliferative effects of 3-Butylidenephthalide (n-Butylidenephthalide; BP) on cells from GBM, neuroblastoma, lung cancer, melanoma, teratoma, leukemia, breast cancer and hepatocellular carcinoma, as well as from normal fibroblast and vascular endothelial cells, were determined. The IC50 values of BP after a 48 h incubation with tumor cell lines (IC50: 15–67 μg/mL) were significantly lower than the values for normal fibroblast cells (IC50: >?100 μg/mL, p < 0.0001) or carmustine (BCNU)-treated tumor cells (IC50: 40 ～ 100 μg/mL, p < 0.001; Table 1). In the two normal cell types, vascular endothelial cells (IC50 = 25.0 ± 2.0 μg/mL) were more sensitive to BP than fibroblast cells (IC50 > 100 μg/mL) (p < 0.0001). These experiments showed that BP could induce high cytotoxicity against brain and other tumour cells but only low or no cytotoxicity against normal fibroblast cells.

• 安全性プロファイル

  Moderately toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

3-ブチリデンフタリド 上流と下流の製品情報

3-ブチリデンフタリド 生産企業

Global(300)Suppliers

3-ブチリデンフタリド スペクトルデータ(¹HNMR、FT-IR)

551-08-6, 3-ブチリデンフタリド キーワード