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3-Chloro-2-methylpropene

Description

CAS No.563-47-3
Chemical Name:3-Chloro-2-methylpropene
CBNumber:CB9402043
Molecular Formula:C4H7Cl
Formula Weight:90.55
MOL File:563-47-3.mol

3-Chloro-2-methylpropene Property

Melting point -80 °C (lit.)
Boiling point 71-72 °C (lit.)
Density 0.925 g/mL at 20 °C (lit.)
vapor density 3.12 (vs air)
vapor pressure 102 mm Hg ( 20 °C)
refractive index n20/D 1.427(lit.)
Flash point 9 °F
storage temp. 2-8°C
solubility H2O: insoluble
form Liquid
color Clear
explosive limit 2.2-10.4%(V)
Water Solubility 0.5 g/L (20 ºC)
Merck 14,2148
BRN 878160
CAS DataBase Reference 563-47-3(CAS DataBase Reference)
EWG's Food Scores 3-4
FDA UNII 7A9X1C3I3O
Proposition 65 List 3-Chloro-2-methylpropene
IARC 2B (Vol. 63, 115) 2018
NIST Chemistry Reference 1-Propene, 3-chloro-2-methyl-(563-47-3)
EPA Substance Registry System 3-Chloro-2-methyl-1-propene (563-47-3)
UNSPSC Code 12352101
NACRES NA.22

Safety

Hazard Codes :F,C,N
Risk Statements :11-20/22-34-43-51/53
Safety Statements :9-16-29-36/37/39-45-61-26
RIDADR :UN 2554 3/PG 2
WGK Germany :2
RTECS :UC8050000
Autoignition Temperature :899 °F
TSCA :Yes
HazardClass :3
PackingGroup :II
HS Code :29032900
Hazardous Substances Data :563-47-3(Hazardous Substances Data)

NFPA 704:

	3
2		1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H225-H302+H332-H314-H317-H411
Precautionary statements P210-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

3-Chloro-2-methylpropene Price More Price(14)

Brand: Sigma-Aldrich(India)
Product number: 8.05905
Product name : 3-Chloro-2-methyl-1-propene
Purity: for synthesis
Packaging: 100ML
Price: ₹2399.99
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 8.05905
Product name : 3-Chloro-2-methyl-1-propene
Purity: for synthesis
Packaging: 500ML
Price: ₹4690.01
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich
Product number: 281972
Product name : 3-Chloro-2-methyl-1-propene
Purity: contains ~250?ppm Pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) as stabilizer, 98%
Packaging: 100ML
Price: ₹2954
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 281972
Product name : 3-Chloro-2-methyl-1-propene
Purity: contains ~250?ppm Pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) as stabilizer, 98%
Packaging: 100ML
Price: ₹2954
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich
Product number: 281972
Product name : 3-Chloro-2-methyl-1-propene
Purity: contains ~250?ppm Pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) as stabilizer, 98%
Packaging: 1L
Price: ₹13271.9
Updated: 2022/06/14
Buy: Buy

3-Chloro-2-methylpropene Chemical Properties,Usage,Production

Description 3-Chloro-2-methylpropene is used as an intermediate to produce carbofuran, herbicides, plastics, pharmaceuticals and other organics. It is also used as an additive in textile and perfumes. It was used to study ring opening polymerization of oxirane derivatives using organotin phosphate condensate and cationic polymerization of 3-Chloro-2-methylpropene with AICI3 and AIBr3 as initiators. It is also the reactant for the synthesis of cyclobutanone.
Chemical Properties clear liquid
Uses 3-Chloro-2-methyl-1-propene was used to study ring opening polymerization of oxirane derivatives using organotin phosphate condensate. It was used to study cationic polymerization of 3-Chloro-2-methyl-1-propene using using AICI₃ and A₃IBr, as initiators.
Uses In organic synthesis.
Uses 3-Chloro-2-methylpropene has been used as reactant in the synthesis of cyclobutanone. It is used as an intermediate in the production of plastics, pharmaceuticals and other organic chemicals.
Definition ChEBI: 3-Chloro-2-methylpropene is an organochlorine compound.
Biological Functions MAC is a valuable index for clinical anesthesia, but it is seldom employed without taking other factors into consideration. For example, inhibiting movement in only 50% of patients is not acceptable. Consequently, if an inhalational agent were being used alone—that is, without the administration of other anesthetics or analgesic drugs—the anesthesiologist would employ a multiple of its MAC value to ensure immobility.MAC is frequently multiplied by a factor of 1.3 to achieve nearly 100% clinical efficacy. On the other hand, useful clinical results may be achieved with doses of anesthetics below MAC levels. For example, mild analgesia and amnesia often occur with doses of inhalational agents that are near 0.5 MAC. In this state, it may even be possible to communicate with patients intraoperatively, while their recall is limited.
Synthesis Reference(s) The Journal of Organic Chemistry, 46, p. 824, 1981 DOI: 10.1021/jo00317a041
General Description A colorless to straw-colored liquid with a sharp penetrating odor. Less dense than water and insoluble in water. Flash point below 0°F. May be toxic by ingestion. Irritating to skin and eyes. Used to make plastics and pharmaceuticals.
Air & Water Reactions Highly flammable. 3-Chloro-2-methylpropene may react with water at elevated temperatures. . Insoluble in water.
Reactivity Profile 3-Chloro-2-methylpropene is sensitive to light. 3-Chloro-2-methylpropene can react vigorously with oxidizers. 3-Chloro-2-methylpropene is incompatible with strong bases. 3-Chloro-2-methylpropene may react with water at elevated temperatures. .
Hazard Irritant; poison; anesthetic; questionable carcinogen; toxic.
Health Hazard Inhalation causes irritation of nose and throat. Contact of vapor or liquid with eyes causes irritation. Liquid irritates skin. Ingestion causes irritation of mouth and stomach.
Safety Profile Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Experimental reproductive effects. An irritant. Human mutation data reported. Very dangerous fire hazard when exposed to heat, flame, or oxidizers. Moderately explosive when exposed to heat or flame. Can react vigorously with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and ALLYL COMPOUNDS.
Carcinogenicity 3-Chloro-2-methylpropene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Toxics Screening Level The initial risk screening level (IRSL) is 0.03μg/m3 with an annual averaging time.